In several issues of this newsletter, we have included several papers on the topic of the C–-H direct functionalization. There has been an increasing interest in this field and the number of papers published grows each month. Bellina and Rossi have just published a review covering recent advances on the functionalization of heteroarene C–H bonds with aryl halides, pseudohalides, trifluoroborates, and iodonium salts. A quick way for medicinal chemists to keep in touch with this topic.
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