Review of the month : 2-Iodoxybenzoic acid (IBX)

For many chemists around the IBX is just another oxidant, and one with a bad reputation. Once seen only as a precursor of the famous Dess-Martin Periodinane, it has now many applications in chemistry and not only as mild oxidant of alcohols. The review “2-Iodoxybenzoic acid (IBX): an efficient hypervalent iodine reagent” by Satam et al. covers the multiple uses of this reagent as oxidant, promoter of heterocyclic compounds, deprotection and cleavage reagent and many others.

2-Iodoxybenzoic acid (IBX): an efficient hypervalent iodine reagent
Tetrahedron 2010, 66 (39) (8), pp 7659–7706.
See: 10.1016/j.tet.2010.07.014